Polypharmacy

Antihistamines A common Contributor In Opioid Overdose Deaths?

A recent analysis by the CDC and published in Morbidity And Mortality Weekly Reports has shown that antihistamines play a role in the growing drug overdose crisis. Of the total US drug overdose deaths reported to the CDC from 2019 to 2020, 13,574 (14.79%) involved antihistamine positivity. First-generation H1 subtype antihistamines, such as diphenhydramine, made …

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The Fourth Wave Of The Opiate Crisis

For over two decades, the opioid crisis in the United States has been an urgent health care emergency. Initially driven by over-prescription of pharmaceutical opioids, this has evolved into a “fourth wave” marked by poly-substance use, combining opioids and methamphetamine, resulting in record-high deaths year after year. The Covid-19 pandemic has made the situation even …

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