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Thank you for the review. When used in combination with a benzo (I prefer alprazolam) this drug combo produces pre-op anxiolysis and sedation. When supplemented with N2O/O2 hypnosis can be achieved. When combined with a standard TIVA technique overall doses are decreased when titrated to the desired endpoint resulting in faster recovery and overall a more smoother level of anesthesia. Because of sympathetic down regulation patients are calmer and rarely does the patient develop shivering.
When used judiciously and carefully this is a great adjunct.